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Article

Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs.

Molecular and cellular biology - 1 Oct 2003

Mitchell Philip, Petfalski Elisabeth, Houalla Rym, Podtelejnikov Alexandre, Mann Matthias, Tollervey David

Abstract excerpt

Related exosome complexes of 3'-->5' exonucleases are present in the nucleus and the cytoplasm. Purification of exosome complexes from whole-cell lysates identified a Mg(2+)-labile factor present in substoichiometric amounts. This protein was identified as the nuclear protein Yhr081p, the homologue of human C1D, which we have designated Rrp47p (for rRNA processing). Immunoprecipitation of epitope-tagged Rrp47p...

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Identifiers

PMID: 12972615
DOI: 10.1128/MCB.23.19.6982-6992.2003
PMCID: PMC193929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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