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Article

Direct and indirect effects of retinoic acid on human Th2 cytokine and chemokine expression by human T lymphocytes

21 Nov 2006

Abstract excerpt

BACKGROUND: Vitamin A (VA) deficiency induces a type 1 cytokine response and exogenously provided retinoids can induce a type 2 cytokine response both in vitro and in vivo. The precise mechanism(s) involved in this phenotypic switch are inconsistent and have been poorly characterized in humans. In an effort to determine if retinoids are capable of inducing Th2 cytokine responses in human T cell cultures, we...

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PMID: 17118196
DOI: 10.1186/1471-2172-7-27

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