Article
CLOCK gene T3111C polymorphism is associated with Japanese schizophrenics: a preliminary study.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Mar 2007
Takao T, Tachikawa H, Kawanishi Y, Mizukami K, Asada T
Abstract excerpt
The CLOCK gene has attracted attention due to its influence on the circadian rhythm, as well as its impacts on the dopaminergic system. We conducted a preliminary study to examine whether the T3111C single nucleotide polymorphism of the CLOCK gene is associated with the development of schizophrenia by examining samples from schizophrenics (n=145) and normal controls (n=128). Both genotype and allele frequencies...
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