Association of intron 1 variants of the dopamine transporter gene with schizophrenia.

doi:10.1016/j.neulet.2012.02.015

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Article

Association of intron 1 variants of the dopamine transporter gene with schizophrenia.

Neuroscience letters - 4 Apr 2012

Zheng Chunming, Shen Yan, Xu Qi

Abstract excerpt

The dopamine transporter (DAT1) gene has been implicated in the pathogenesis of many neuropsychiatric disorders, including schizophrenia. The present study aimed to investigate association of the DAT1 gene polymorphisms with schizophrenia in a Han Chinese population. Two single nucleotide polymorphisms (SNPs) in the DAT1 gene (rs2975223 and rs2455391) were tested in 368 patients with schizophrenia and 420 healthy...

Topics

Adolescent
Adult
Alleles
Dopamine Plasma Membrane Transport Proteins
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Haplotypes
Humans
Introns
Male
Middle Aged
Polymorphism, Single Nucleotide
Quantitative Trait Loci
Schizophrenia, Paranoid

Source

Open in PubMed

Identifiers

PMID: 22366190
DOI: 10.1016/j.neulet.2012.02.015

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