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Article

Biophysical characterisation of the small ankyrin repeat protein myotrophin.

Journal of molecular biology - 26 Jan 2007

Lowe Alan R, Itzhaki Laura S

Abstract excerpt

The 118 residue protein myotrophin is composed of four ankyrin repeats that stack linearly to form an elongated, predominantly alpha-helical structure. The protein folds via a two-state mechanism at equilibrium. The free energy change of unfolding in water (DeltaG(U-N)(H(2)O)) is 5.8 kcal.mol(-1). The chevron plot reveals that the folding reaction has a broad energy barrier and that it conforms to a two-state...

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Identifiers

PMID: 17113103
DOI: 10.1016/j.jmb.2006.10.060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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