Article
Accumulation of deleterious mutations in small abiotic populations of RNA.
Genetics - 1 Jan 2007
Soll Steven J, Díaz Arenas Carolina, Lehman Niles
Abstract excerpt
The accumulation of slightly deleterious mutations in populations leads to the buildup of a genetic load and can cause the extinction of populations of small size. Mutation-accumulation experiments have been used to study this process in a wide variety of organisms, yet the exact mutational underpinnings of genetic loads and their fitness consequences remain poorly characterized. Here, we use an abiotic system of...
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