Article
Exposed epitopes on a Trypanosoma equiperdum variant surface glycoprotein altered by point mutations.
The EMBO journal - 1 Jul 1991
Baltz T, Giroud C, Bringaud F, Eisen H, Jacquemot C, Roth C W
Abstract excerpt
African trypanosomes are covered by a dense protein layer that is immunologically distinct on different trypanosome isolates and is termed the variant surface glycoprotein (VSG). The different VSGs are expressed in a general order, where some VSGs appear preferentially early in infection and others only later. The exposed epitopes on a late antigen, VSG 78, of T.equiperdum were studied by the technique of...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antigenic Variation
- Antigens, Protozoan
- Base Sequence
- Epitopes
- Molecular Sequence Data
- Mutation
- Trypanosoma
- Variant Surface Glycoproteins, Trypanosoma