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Stem cells and the evolving notion of cellular identity

30 Sept 2015

Abstract excerpt

Stem cells are but one class of the myriad types of cells within an organism. With potential to self-renew and capacity to differentiate, stem cells play essential roles at multiple stages of development. In the early embryo, pluripotent stem cells represent progenitors for all tissues while later in development, tissue-restricted stem cells give rise to cells with highly specialized functions. As best understood...

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PMID: 26416685
DOI: 10.1098/rstb.2014.0376

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