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Identification of brain neurons expressing the dopamine D4 receptor gene using BAC transgenic mice

1 Nov 2006

Abstract excerpt

The dopamine D4 receptor (D4R) has received considerable interest because of its higher affinity for atypical antipsychotics, the extremely polymorphic nature of the human gene and the genetic association with attention deficit and hyperactivity disorder (ADHD). Several efforts have been undertaken to determine the D4R expression pattern in the brain using immunohistochemistry, binding autoradiography and in situ...

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PMID: 17100831
DOI: 10.1111/j.1460-9568.2006.05148.x

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