Article
Variations in the thrombomodulin and endothelial protein C receptor genes in couples with recurrent miscarriage.
Human reproduction (Oxford, England) - 1 Mar 2007
Kaare M, Ulander V-M, Painter J N, Ahvenainen T, Kaaja R, Aittomäki K
Abstract excerpt
BACKGROUND: Recurrent miscarriage (RM) has been suggested to be caused by mutations in genes coding for various coagulation factors resulting in thrombophilia. Mouse models indicate that genes involved in the protein C anticoagulant pathway are essential for normal embryonic development. Loss of...
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