Article
Analysis of C3 Gene Variants in Patients With Idiopathic Recurrent Spontaneous Pregnancy Loss.
Frontiers in immunology - 1 Jan 2018
Mohlin Frida C, Gros Piet, Mercier Eric, Gris Jean-Christophe Raymond, Blom Anna M
Abstract excerpt
Miscarriage is the most common complication of pregnancy. Approximately 1% of couples trying to conceive will experience recurrent miscarriages, defined as three or more consecutive pregnancy losses and many of these cases remain idiopathic. Complement is implicated both in the physiology and pathology of pregnancy. Therefore, we hypothesized that alterations in the C3 gene could potentially predispose to this...
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