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Article

Paternal thrombophilic gene mutations are not associated with recurrent miscarriage.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Oct 2008

Toth Bettina, Vocke Franziska, Rogenhofer Nina, Friese Klaus, Thaler Christian J, Lohse Peter

Abstract excerpt

PROBLEM: Recurrent miscarriage (RM) affects 1-3% of couples. So far, diagnostic procedures are performed only in female patients. However, the main part of the placentary perfusion is encoded by both the maternal and the paternal genome. METHOD OF STUDY: In this case-control study, German couples with two (n = 49) or three and more RM (n = 102) and 157 German control couples were analyzed for the factor V-Leiden...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18754836
DOI: 10.1111/j.1600-0897.2008.00630.x

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paternal thrombophilic gene mutations are not associated with recurrent miscarriage.PMID 18754836Read ↗

Genetic thrombophilic mutations among couples with recurrent miscarriage.Semantic proximity Read ↗

Maternal factor V Leiden and prothrombin mutations do not seem to contribute to the occurrence of two or more than two consecutive miscarriages in Caucasian patients.Semantic proximity Read ↗

A Pilot Study on Multigenic Thrombophilic Risk in Recurrent Pregnancy Loss: Interactions Between MTHFR Polymorphisms and Classical Thrombophilia-Associated SNPs.Semantic proximity Read ↗

Factor V Leiden and prothrombin G20210A in Portuguese women with recurrent miscarriage: is it worthwhile to investigate?Semantic proximity Read ↗

Thrombophilias and recurrent pregnancy loss: a critical appraisal of the literature.Semantic proximity Read ↗

Recurrent miscarriage is not associated with a higher prevalence of inherited and acquired thrombophilia.Semantic proximity Read ↗

A prospective case-control study analyzes 12 thrombophilic gene mutations in Turkish couples with recurrent pregnancy loss.Semantic proximity Read ↗

Maternal inherited thrombophilia and recurrent pregnancy loss: a Tunisian study and review of literature.Semantic proximity Read ↗

Factor V Leiden and prothrombin G20210A mutations, but not methylenetetrahydrofolate reductase C677T, are associated with recurrent miscarriagesSemantic proximity Read ↗

Lack of association between thrombophilic gene variants and recurrent pregnancy loss.Semantic proximity Read ↗

Multiple thrombophilic gene mutations rather than specific gene mutations are risk factors for recurrent miscarriage.Semantic proximity Read ↗

G20210A prothrombin gene mutation: prevalence in a recurrent miscarriage population.Semantic proximity Read ↗

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