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Article

Mutations in the palm region of a plus-strand RNA virus polymerase result in attenuated phenotype.

The Journal of general virology - 1 Dec 2006

Gallei Andreas, Widauer Simone, Thiel Heinz-Jürgen, Becher Paul

Abstract excerpt

The three-dimensional structure of RNA-dependent RNA polymerases (RdRps) is highly conserved among RNA viruses. In a previous study, a unique set of mutant strains of Bovine viral diarrhea virus was obtained, encompassing either a genomic deletion of six codons or duplications of between 1 and 45...

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Identifiers

PMID: 17098978
DOI: 10.1099/vir.0.81809-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17098978-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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