Article
Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies.
The Journal of biological chemistry - 5 Jan 2007
Wang Hong, Gilner Jennifer B, Bautch Victoria L, Wang Da-Zhi, Wainwright Brandon J, Kirby Suzanne L, Patterson Cam
Abstract excerpt
Our recent gene expression profiling analyses demonstrated that Wnt2 is highly expressed in Flk1(+) cells, which serve as common progenitors of endothelial cells, blood cells, and mural cells. In this report, we characterize the role of Wnt2 in mesoderm development during embryonic stem (ES) cell...
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