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Article

FOXK1 regulates Wnt signalling to promote cardiogenesis

10 Apr 2023

Abstract excerpt

AIMS: Congenital heart disease (CHD) is the most common genetic birth defect, which has considerable morbidity and mortality. We focused on deciphering key regulators that govern cardiac progenitors and cardiogenesis. FOXK1 is a forkhead/winged helix transcription factor known to regulate cell cycle kinetics and is restricted to mesodermal progenitors, somites, and heart. In the present study, we define an...

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PMID: 37036809
DOI: 10.1093/cvr/cvad054

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