Article
Recent divergence of the HLA-DRB1*04 allelic lineage from the DRB1*0701 lineage after the separation of the human and chimpanzee species.
Immunogenetics - 1 Mar 2003
Hohjoh Hirohiko, Ohashi Jun, Takasu Miwa, Nishioka Tomoki, Ishida Takafumi, Tokunaga Katsushi
Abstract excerpt
Conventional phylogenetic trees for the human leukocyte antigen (HLA)-DRB1 alleles constructed by the neighbor-joining (Saitou and Nei 1987) and UPGMA (Sneath and Sokal 1973) methods using nucleotide sequences of the DRB1 alleles suggest that DRB1*0701 may have diverged from other DRB1 alleles before the separation of the human and chimpanzee species, because of a large number of nucleotide changes in DRB1*0701...
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