Restoration of the epidermal phenotype by follicular outer root sheath cells in recombinant culture with dermal fibroblasts.

doi:10.1016/0014-4827(91)90357-z

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Article

Restoration of the epidermal phenotype by follicular outer root sheath cells in recombinant culture with dermal fibroblasts.

Experimental cell research - 1 Jun 1991

Limat A, Breitkreutz D, Hunziker T, Boillat C, Wiesmann U, Klein E, Noser F, Fusenig N E

Abstract excerpt

In order to better understand how outer root sheath (ORS) cells are able to reepithelialize superficial skin wounds, the level of epidermal differentiation achieved by isolated ORS cells in vitro was determined. Using postmitotic human dermal fibroblasts (HDF) as efficient feeder cells, large numbers of ORS cells from individual follicles were generated. Passaged ORS cells were grown exposed to air on...

Topics

Adult
Antigens, Surface
Biomarkers
Cell Communication
Cell Differentiation
Epidermal Cells
Epidermis
Fibroblasts
Filaggrin Proteins
Fluorescent Antibody Technique
Hair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Intermediate Filament Proteins

Keratins

Laminin

Microscopy, Electron

Middle Aged

Organelles

Source

Open in PubMed

Identifiers

PMID: 1709101
DOI: 10.1016/0014-4827(91)90357-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1709101-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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