Article
Denatured collagen modulates the phenotype of normal and wounded human skin equivalents.
The Journal of investigative dermatology - 1 Jul 2008
Egles Christophe, Shamis Yulia, Mauney Joshua R, Volloch Vladimir, Kaplan David L, Garlick Jonathan A
Abstract excerpt
Epithelial-mesenchymal interactions are known to play an important role in modulating homeostasis and repair. However, it remains unclear how the composition of the extracellular matrix may regulate the ability of dermal fibroblasts to engage in such cross talk. To address this, we studied how fibroblast phenotype was linked to the behavior of normal and wounded human skin equivalents (HSE) by comparing human...
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