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Novel replication complex architecture in rubella replicon-transfected cells

3 Nov 2006

Abstract excerpt

Rubella virus (RUB) assembles its replication complexes (RCs) in modified organelles of endo-lysosomal origin, known as cytopathic vacuoles (CPVs). These peculiar structures are key elements of RUB factories, where rough endoplasmic reticulum, mitochondria, and Golgi are recruited. Bicistronic RUB replicons expressing an antibiotic resistance gene either in the presence or the absence of the RUB capsid (C) gene...

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PMID: 17087733
DOI: 10.1111/j.1462-5822.2006.00837.x

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