Article
Dopamine transporter is enriched in filopodia and induces filopodia formation.
Molecular and cellular neurosciences - 1 Sept 2015
Caltagarone John, Ma Shiqi, Sorkin Alexander
Abstract excerpt
Dopamine transporter (DAT, SLC6A3) controls dopamine (DA) neurotransmission by mediating re-uptake of extracellular DA into DA neurons. DA uptake depends on the amount of DAT at the cell surface, and is therefore regulated by DAT subcellular distribution. Hence we used spinning disk confocal microscopy to demonstrate DAT localization in membrane protrusions that contained filamentous actin and myosin X (MyoX), a...
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