Article
Nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions.
Cancer - 1 Dec 2006
Tang Ximing, Liu Diane, Shishodia Shishir, Ozburn Natalie, Behrens Carmen, Lee J Jack, Hong Waun Ki, Aggarwal Bharat B, Wistuba Ignacio I
Abstract excerpt
BACKGROUND: Nuclear factor-kappaB (NF-kappaB), a key transcription factor thought to play a major role in carcinogenesis, regulates many important signaling pathways involved in tumor promotion. Although NF-kappaB can be activated in lung cancer cell lines by tobacco exposure, there have been no studies of the expression of NF-kappaB in lung cancer pathogenesis. METHODS: The immunohistochemical expression of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.