Nuclear Factor-κB in Development, Prevention, and Therapy of Cancer

Abstract excerpt

Nuclear factor-kappaB (NF-kappaB) is a signal transcription factor that has emerged as an important modulator of altered gene programs and malignant phenotype in development of cancer. Major carcinogens and oncogenic viruses induce NF-kappaB activation, and a variety of subsequent oncogenic events contribute to a progressive increase in constitutive NF-kappaB activation as an important common pathway in most...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Natural Compounds in Disease Treatment
• Share to Natural product bioactivities and synthesis
• Share to NF-κB Signaling Pathways