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Article

NF-kappaB in Lung Tumorigenesis

14 Dec 2011

Abstract excerpt

The development of lung cancer in humans can be divided into three steps: initiation, promotion and progression. This process is driven by alterations in related signal transduction pathways. These pathways signal the aberrant activation of NF-kappaB, a transcription factor that regulates the expression of genes important for lung tumorigenesis. Our current knowledge about the role of the NF-kappaB signaling...

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PMID: 24213137
DOI: 10.3390/cancers3044258

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