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Article

Function of Nuclear Factor Kappa B (NF-kB) in Human Diseases-A Review

2016-10-01

Abstract excerpt

Nuclear factor kappa B (NFkB) is a transcription factor that resides in the cytoplasm of every cell and translocates to the nucleus when activated. Its activation is induced by a wide variety of agents including stress, cigarette smoke, viruses, bacteria, inflammatory stimuli, cytokines, free radicals, carcinogens, tumor promoters and endotoxins. On activation, NFkB regulates the expression of almost 400 different...

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Identifiers and source

Literature Corpus work
6ed19176-88fa-51b6-b58d-8c0ac1759fdf
DOI
10.22205/sijbs/2016/v2/i4/103443
Open publication

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