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Article

Immunolabeling demonstrates the interdependence of mouse brain alpha4 and beta2 nicotinic acetylcholine receptor subunit expression.

The Journal of comparative neurology - 20 Dec 2006

Whiteaker Paul, Cooper John F, Salminen Outi, Marks Michael J, McClure-Begley Tristan D, Brown Robert W B, Collins Allan C, Lindstrom Jon M

Abstract excerpt

Immunolabeling of beta2 and alpha4 subunits was quantitated in brain sections (14 mum) using [(125)I]mAb 270 and [(125)I]mAb 299, respectively. Specificity was demonstrated by signal loss in beta2(-/-) and alpha4(-/-) brain sections, respectively. Even mild paraformaldehyde fixation severely affected immunolabeling, so this study used unfixed sections. Immunolabeling autoradiography was used to map and quantitate...

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Identifiers

PMID: 17072836
DOI: 10.1002/cne.21181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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