Article
Mutations in the NF-kappaB signaling pathway: implications for human disease.
Oncogene - 30 Oct 2006
Courtois G, Gilmore T D
Abstract excerpt
The nuclear factor-kappa B (NF-kappaB) signaling pathway is a multi-component pathway that regulates the expression of hundreds of genes that are involved in diverse and key cellular and organismal processes, including cell proliferation, cell survival, the cellular stress response, innate immunity and inflammation. Not surprisingly, mis-regulation of the NF-kappaB pathway, either by mutation or epigenetic...
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