Article
DNA cleavage mediated by copper superoxide dismutase via two pathways.
Journal of inorganic biochemistry - 1 Feb 2007
Han Yingchun, Shen Tao, Jiang Wei, Xia Qingfeng, Liu Changlin
Abstract excerpt
The known action of Cu, Zn superoxide dismutase (Cu(2)Zn(2)SOD) that converts O(2)(-) to O(2) and H(2)O(2) plays a crucial role in protecting cells from toxicity of oxidative stress. However, the overproduction of Cu(2)Zn(2)SOD does not result in increased protection but rather creates a variety...
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