Demonstration of a transcription element in vitro between the capping site and translation initiation site of the mouse myelin basic protein gene.

doi:10.1016/0014-5793(91)80207-j

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Article

Demonstration of a transcription element in vitro between the capping site and translation initiation site of the mouse myelin basic protein gene.

FEBS letters - 11 Mar 1991

Tamura T, Mikoshiba K

Abstract excerpt

A transcription element was identified, by in vitro analyses, just downstream from the capping site of the mouse myelin basic protein (MBP) gene. Deletion of this element caused a dramatic drop of transcription efficiency in mouse brain, rat liver and HeLa cell nuclear extracts, regardless of the form of DNA being closed circular or linear form. DNase I footprint analysis demonstrated the presence of a ubiquitous...

Topics

Animals
Base Sequence
Deoxyribonuclease I
Gene Expression Regulation
HeLa Cells
Mice
Molecular Sequence Data
Mutation
Myelin Basic Protein
Protein Biosynthesis
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptor Aggregation

Regulatory Sequences, Nucleic Acid

Repetitive Sequences, Nucleic Acid

TATA Box

Trans-Activators

Transcription, Genetic

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Open in PubMed

Identifiers

PMID: 1707012
DOI: 10.1016/0014-5793(91)80207-j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1707012-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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