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Article

Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia.

Blood - 1 Mar 2007

Malinge Sebastien, Ben-Abdelali Raouf, Settegrana Catherine, Radford-Weiss Isabelle, Debre Marianne, Beldjord Kheira, Macintyre Elizabeth A, Villeval Jean-Luc, Vainchenker William, Berger Roland, Bernard Olivier A, Delabesse Eric, Penard-Lacronique Virginie

Abstract excerpt

Activation of tyrosine kinase genes is a frequent event in human hematologic malignancies. Because gene activation could be associated with gene dysregulation, we attempted to screen for activating gene mutation based on high-level gene expression. We focused our study on the Janus kinase 2 (JAK2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17068151
DOI: 10.1182/blood-2006-09-045963

Genes

JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17068151-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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