Article
Identification of ethanol responsive domains of adenylyl cyclase.
Alcoholism, clinical and experimental research - 1 Nov 2006
Yoshimura Masami, Pearson Susan, Kadota Yoichi, Gonzalez Cristina E
Abstract excerpt
BACKGROUND: The activity of adenylyl cyclase (AC) is enhanced by pharmacologically relevant concentrations of ethanol. The enhancing effect of ethanol on AC activity is AC isoform-specific. Therefore, we hypothesized that within a cyclic AMP-generating system, AC is the target of ethanol's action...
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