Article
A muscle-specific intron enhancer required for rescue of indirect flight muscle and jump muscle function regulates Drosophila tropomyosin I gene expression.
Molecular and cellular biology - 1 Apr 1991
Schultz J R, Tansey T, Gremke L, Storti R V
Abstract excerpt
The control of expression of the Drosophila melanogaster tropomyosin I (TmI) gene has been investigated by P-element transformation and rescue of the flightless and jumpless TmI mutant strain, Ifm(3)3. To localize cis-acting DNA sequences that control TmI gene expression, Ifm(3)3 flies were transformed with P-element plasmids containing various deletions and rearrangements of the TmI gene. The effects of these...
Topics
- Animals
- DNA Transposable Elements
- Drosophila melanogaster
- Enhancer Elements, Genetic
- Gene Expression Regulation
- Introns
- Muscles
- Mutation
- Phenotype
- RNA
- Restriction Mapping