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Article

Foxf2: a novel locus for anterior segment dysgenesis adjacent to the Foxc1 gene.

PloS one - 1 Jan 2011

McKeone Richard, Vieira Helena, Gregory-Evans Kevin, Gregory-Evans Cheryl Y, Denny Paul

Abstract excerpt

Anterior segment dysgenesis (ASD) is characterised by an abnormal migration of neural crest cells or an aberrant differentiation of the mesenchymal cells during the formation of the eye's anterior segment. These abnormalities result in multiple tissue defects affecting the iris, cornea and drainage structures of the iridocorneal angle including the ciliary body, trabecular meshwork and Schlemm's canal. In some...

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Source

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Identifiers

PMID: 22022403
DOI: 10.1371/journal.pone.0025489
PMCID: PMC3192754

Genes

FOXC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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