Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets

Abstract excerpt

Abstract Non-typhoidalSalmonella(NTS) are highly prevalent food-borne pathogens. Recently, a highly invasive, multi-drug resistantS. Typhimurium, ST313, emerged as a major cause of bacteraemia in children and immunosuppressed adults, however the pathogenic mechanisms remain unclear. Here, we utilize invasive and non-invasiveSalmonellastrains combined with single-cell RNA-sequencing to study the transcriptome of...

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