Article
Competitive displacement of DNA during surface hybridization.
Biophysical journal - 1 Jan 2007
Bishop J, Wilson C, Chagovetz A M, Blair S
Abstract excerpt
Using real-time dual-color fluorescence detection, we have experimentally tracked individual target species during competitive DNA surface hybridization in a two-component sample. Our experimental results demonstrate displacement of the lower affinity species by the higher affinity species and corroborate recent theoretical models describing competitive DNA surface hybridization. Competition at probe sites...
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