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Article

Reversion of tumor phenotype in surface transplants of skin SCC cells by scaffold-induced stroma modulation.

Carcinogenesis - 1 Mar 2007

Willhauck Michael J, Mirancea Nicolae, Vosseler Silvia, Pavesio Alessandra, Boukamp Petra, Mueller Margareta M, Fusenig Norbert E, Stark Hans-Jürgen

Abstract excerpt

Interactions between cancer cells and the tissue microenvironment play an essential role in controlling tumor development and progression. Here, we report that stromal modulation induced by a biodegradable meshwork (Hyalograft 3D) inhibited tumor vascularization and invasion of the locally invasive low-grade malignant human HaCaT-ras II-4 keratinocytes in a surface xenotransplantation assay. The scaffold caused...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17056607
DOI: 10.1093/carcin/bgl188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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