Article
Enhanced chemoresistance of squamous carcinoma cells grown in 3D cryogenic electrospun scaffolds.
Biomedical materials (Bristol, England) - 1 Oct 2013
Bulysheva Anna A, Bowlin Gary L, Petrova Stella P, Yeudall W Andrew
Abstract excerpt
It is critically important to study head and neck squamous cell carcinoma tumorigenic mechanisms in order to gain a better understanding of tumor development, progression, and treatment. Unfortunately, a representative three-dimensional (3D) model for these evaluations has yet to be developed. The purpose of this study was to replicate tumor extracellular matrix (ECM) morphology utilizing electrospinning...
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