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Article

A novel locus for idiopathic generalized epilepsy in French-Canadian families maps to 10p11.

American journal of medical genetics. Part A - 1 Mar 2008

Kinirons Peter, Verlaan Dominique J, Dubé Marie-Pierre, Poirier Josée, Deacon Charles, Lortie Anne, Clément Jean-François, Desbiens Richard, Carmant Lionel, Cieuta-Walti Cecile, Shevell Michael, Rouleau Guy A, Cossette Patrick

Abstract excerpt

Idiopathic generalized epilepsy (IGE) has evidence of a strong genetic etiology. We conducted genomewide linkage analysis for genes responsible for familial IGE in French-Canadian pedigrees. Twenty families segregating autosomal dominant epilepsy were collected. Four larger IGE families sufficiently powerful for independent linkage analysis were genome-scanned and follow-up fine mapping was performed over regions...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18241056
DOI: 10.1002/ajmg.a.32139

Genes

NRP1
PARD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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