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Article

Rodent diet aids and the fallacy of caloric restriction

19 Oct 2021

Abstract excerpt

Understanding the molecular mechanisms of normal aging is a prerequisite to significantly improving human health span. Caloric restriction (CR) can delay aging and has served as a yardstick to evaluate interventions extending life span. However, mice given unlimited access to food suffer severe obesity. Health gains from CR depend on control mice being sufficiently overweight and less obese mouse strains benefit...

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PMID: 34673082
DOI: 10.1016/j.mad.2021.111584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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