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Article

Polymorphisms of the<i>ABCB1</i>Gene are Associated with the Therapeutic Response to Risperidone in Chinese Schizophrenia Patients

1 Oct 2006

Abstract excerpt

P-glycoprotein, a product of the ATP-binding cassette B1 (ABCB1) gene, plays an important role in absorption and distribution of drugs. The brain entry of risperidone and 9-OH-risperidone is greatly limited by P-glycoprotein, which implies that the functional polymorphisms of ABCB1 in humans may be a factor contributing to the variability in response to risperidone. The present study was therefore designed to...

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Identifiers

PMID: 17054409
DOI: 10.2217/14622416.7.7.987

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Polymorphisms of the<i>ABCB1</i>Gene are Associated with the Therapeutic Response to Risperidone in Chinese Schizophrenia PatientsPMID 17054409Read ↗

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