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Article

Urocortin 2 modulates glucose utilization and insulin sensitivity in skeletal muscle.

Proceedings of the National Academy of Sciences of the United States of America - 31 Oct 2006

Chen Alon, Brar Bhawanjit, Choi Cheol Soo, Rousso David, Vaughan Joan, Kuperman Yael, Kim Shee Ne, Donaldson Cindy, Smith Sean M, Jamieson Pauline, Li Chien, Nagy Tim R, Shulman Gerald I, Lee Kuo-Fen, Vale Wylie

Abstract excerpt

Skeletal muscle is the principal tissue responsible for insulin-stimulated glucose disposal and is a major site of peripheral insulin resistance. Urocortin 2 (Ucn 2), a member of the corticotropin-releasing factor (CRF) family, and its cognate type 2 CRF receptor (CRFR2) are highly expressed in s...

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Identifiers

PMID: 17050686
DOI: 10.1073/pnas.0607337103
PMCID: PMC1637624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17050686-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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