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Article

Enhanced insulin-like growth factor-I (IGF-I) cell association at reduced pH is dependent on IGF binding protein-3 (IGFBP-3) interaction.

Journal of cellular physiology - 1 Feb 2007

Forsten-Williams Kimberly, Cassino Theresa R, Delo Laura J, Bellis Abigail D, Robinson Anne S, Ryan Thomas E

Abstract excerpt

The cellular microenvironment impacts how signals are transduced by cells and plays a key role in tissue homeostasis. Although pH is generally well regulated, there are a number of situations where acidosis occurs and our work addresses how low pH impacts cell association of insulin-like growth f...

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PMID: 17044083
DOI: 10.1002/jcp.20849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17044083-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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