Article
Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1.
Molecular and cellular biochemistry - 1 Jan 2007
Guo Wei, Xu Hong, Chen Jing, Yang Yong, Jin Jia Wei, Fu Rui, Liu Hai Mei, Zha Xi Liang, Zhang Zhi Gang, Huang Wen Yan
Abstract excerpt
Prohibitin (PHB), a potential tumor suppressor, has been shown to inhibit cell proliferation by repressing E2F-mediated transcription. But little is known about the role of PHB involved in tubulointerstitial fibrosis (TIF). Here, for the first time, we found PHB protein was positively expressed a...
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