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A novel renal perivascular mesenchymal cell subset gives rise to fibroblasts distinct from classic myofibroblasts

30 Mar 2022

Abstract excerpt

Abstract Perivascular mesenchymal cells (PMCs), which include pericytes, give rise to myofibroblasts that contribute to chronic kidney disease progression. Several PMC markers have been identified; however, PMC heterogeneity and functions are not fully understood. Here, we describe a novel subset of renal PMCs that express Meflin, a glycosylphosphatidylinositol-anchored protein that was recently identified as a...

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PMID: 35354870
DOI: 10.1038/s41598-022-09331-5

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