Mutants in trs120 disrupt traffic from the early endosome to the late Golgi.

Abstract excerpt

Transport protein particle (TRAPP), a large complex that mediates membrane traffic, is found in two forms (TRAPPI and -II). Both complexes share seven subunits, whereas three subunits (Trs130p, -120p, and -65p) are specific to TRAPPII. Previous studies have shown that mutations in the TRAPPII-specific gene trs130 block traffic through or from the Golgi. Surprisingly, we report that mutations in trs120 do not...

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• Share to Endosomes
• Share to Golgi Apparatus
• Share to Guanine Nucleotide Exchange Factors