Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular adaptation and allostery in plant pantothenate synthetases.

The Journal of biological chemistry - 8 Dec 2006

Jonczyk Rafal, Genschel Ulrich

Abstract excerpt

Pantothenate synthetase catalyzes the ATP-dependent condensation of pantoate and beta-alanine to yield pantothenate, the essential precursor to coenzyme A. Bacterial and plant pantothenate synthetases are dimeric enzymes that share significant sequence identity. Here we show that the two-step rea...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Allosteric Regulation
Share to Catalytic Domain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Conserved Sequence

Share to Dimerization

Share to DNA, Plant

Share to Peptide Synthases

Share to Plants

Source

Identifiers

PMID: 17040917
DOI: 10.1074/jbc.M607895200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17040917-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular adaptation and allostery in plant pantothenate synthetases.PMID 17040917Read ↗

Functional plasticity and evolutionary adaptation of allosteric regulation.Semantic proximity Read ↗

Alanine mutation of the catalytic sites of Pantothenate Synthetase causes distinct conformational changes in the ATP binding region.Semantic proximity Read ↗

Distinct Allosteric Networks Underlie Mechanistic Speciation of ABC Transporters.Semantic proximity Read ↗

Plant coenzyme A biosynthesis: characterization of two pantothenate kinases from Arabidopsis.Semantic proximity Read ↗

Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.Semantic proximity Read ↗

Dynamic allostery can drive cold adaptation in enzymes.Semantic proximity Read ↗

Parallel molecular mechanisms for enzyme temperature adaptation.Semantic proximity Read ↗

Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase.Semantic proximity Read ↗

Diversified amino acid-mediated allosteric regulation of phosphoglycerate dehydrogenase for serine biosynthesis in land plants.Semantic proximity Read ↗

Structural evolution of differential amino acid effector regulation in plant chorismate mutases.Semantic proximity Read ↗

Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.Semantic proximity Read ↗

Kinetic and physiological effects of alterations in homologous isocitrate-binding sites of yeast NAD(+)-specific isocitrate dehydrogenase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.