Article
An α‐(1,4)‐amylase is essential for α‐(1,3)‐glucan production and virulence in <i>Histoplasma capsulatum</i>
13 Oct 2006
Abstract excerpt
Histoplasma capsulatum is a dimorphic fungus that causes respiratory and systemic disease and is capable of surviving and replicating within macrophages. The virulence of Histoplasma has been linked to cell wall alpha-(1,3)-glucan; however, the role of this polysaccharide during infection, its organization within the cell wall, and its synthesis and regulation remain poorly understood. To identify genes involved...
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