Article
A kinase-negative mutant of S49 mouse lymphoma cells is defective in posttranslational maturation of catalytic subunit of cyclic AMP-dependent protein kinase.
Molecular and cellular biology - 1 Feb 1991
Steinberg R A
Abstract excerpt
Kinase-negative mutants of S49 mouse lymphoma cells, which lack detectable catalytic (C) subunit of cyclic AMP-dependent protein kinase, nevertheless contain cytoplasmic mRNAs for the two major forms of C subunit, C alpha and C beta. Investigation of the metabolism of C subunits in wild-type and...
Topics
- Amino Acid Sequence
- Animals
- Blotting, Northern
- Cell Line
- Chromatography, Affinity
- Lymphoma
- Macromolecular Substances
- Mice
- Molecular Sequence Data
- Mutation
- Peptides
- Poly A
- Protein Kinases
- Protein Processing, Post-Translational
- RNA
- RNA, Messenger
- RNA, Neoplasm