Article
The Kallmann syndrome gene homolog in C. elegans is involved in epidermal morphogenesis and neurite branching.
Development (Cambridge, England) - 1 Mar 2002
Rugarli Elena I, Di Schiavi Elia, Hilliard Massimo A, Arbucci Salvatore, Ghezzi Cristina, Facciolli Anna, Coppola Giuseppe, Ballabio Andrea, Bazzicalupo Paolo
Abstract excerpt
Kallmann syndrome is an inherited disorder defined by the association of anosmia and hypogonadism, owing to impaired targeting and migration of olfactory axons and gonadotropin-releasing hormone secreting neurons. The gene responsible for the X-linked form of Kallmann syndrome, KAL-1, encodes a secreted protein of still elusive function. It has been proposed that KAL-1 might be involved in some aspects of...
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