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Article

Promoter polymorphisms in matrix metalloproteinases and their inhibitors: few associations with breast cancer susceptibility and progression.

Breast cancer research and treatment - 1 May 2007

Lei Haixin, Hemminki Kari, Altieri Andrea, Johansson Robert, Enquist Kerstin, Hallmans Göran, Lenner Per, Försti Asta

Abstract excerpt

The importance of matrix metalloproteinases and their inhibitors in tumor progression is well documented. We wanted to investigate if single nucleotide polymorphisms (SNPs) in the promoter regions of these genes are associated with susceptibility to or progression of breast cancer. In this, so far largest case-control study, we genotyped eight SNPs in the MMP1, MMP2, MMP3, MMP9, MMP13, RECK and TIMP3 genes in a...

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Source

Identifiers

PMID: 17033924
DOI: 10.1007/s10549-006-9345-2

Genes

MMP9
RECK
TIMP3
MMP2
MMP1
MMP13
MMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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