Article
Murine T cell responses to melittin and its analogs.
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1991
Fehlner P F, Berg R H, Tam J P, King T P
Abstract excerpt
The 26-residue peptide melittin from bee venom elicits high IgG1 and IgE responses in selected strains of mice. The antibody responses were shown previously to be specific mainly for the region of residue 20-26. The T cell epitope of melittin in H-2d-restricted mice is now found to be primarily in residue 11-19, corresponding to an alpha-helical amphiphilic segment of the molecule. Melittin-specific T cell lines...
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